Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-03-28
1997-01-14
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514291, 514332, 514333, 546 89, 546101, 546111, 546255, 546256, 546267, A61K 31435, A61K 3144, C07D491052, C07D22108
Patent
active
055940013
ABSTRACT:
Compounds of Formula (I) have been shown to enhance the release of the neurotransmitter acetylcholine, and thus may be useful in the treatment of diseases of man where subnormal levels of this neurochemical are found, such as in Alzheimer's disease, and other conditions involving learning and cognition. This invention describes compounds, pharmaceutical compositions and methods of treatment comprising compounds of Formula (I): ##STR1##
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DeNoble, et al., Pharmacol. Biochem. Behavior, (1990) 36:957.
Cook, et al., Drug Development Research (1990) 19: 301.
Nickolson, et al., Drug Development Research (1990) 19: 285.
Earl Richard A.
Teleha Christopher A.
Wilkerson Wendell W.
Dentz Bernard
Kondrad Karen H.
The DuPont Merck Pharmaceutical Company
Vance David H.
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