Arylmethylphosphonates and phosphonic acids useful as anti-infla

Details Arylmethylphosphonates and phosphonic acids useful as anti-infla Arylmethylphosphonates and phosphonic acids useful as anti-infla

1995-11-13

1997-01-14

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514 76, 514105, 558162, A61K 3166, A61K 31685, C07F 940, C07F 938

Patent

active

055939805

ABSTRACT:
This invention provides a new use of acids, esters, and salts of arylmethylphosphonates of Formula I, ##STR1## or a phosphonic acid of Formula II ##STR2## and derivatives as anti-inflammatory and anti-arthritic agents. Representative compounds include 4-dodecyloxybenzylphosphonic acid dimethyl ester, (2-naphthalenylmethyl)phosphonic acid dimethyl ester, and ([1,1'-biphenyl]-2-ylmethyl)phosphonic acid dimethyl ester.

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