Benzothiazepine derivatives

Details Benzothiazepine derivatives Benzothiazepine derivatives

1986-08-21

1987-09-15

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540491, A61K 3155, C07D28110

Patent

active

046940022

ABSTRACT:
Calcium channel blocking activity is exhibited by compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein the stereochemistry at the chiral centers in the 3 and 4-positions of the benzothiazepine nucleus is cis, and wherein

REFERENCES:
patent: 3075967 (1963-01-01), Krapcho
patent: 4590188 (1986-05-01), Takeda et al.
Pharmazie, vol. 35, pp. 680-681.
Pharmazie, vol. 38, pp. 827-828.
J. Med. Chem., vol. 9, p. 191, (1966).
J. Med. Chem., vol. 6, p. 544, (1963).
Chem. Pharm. Bull., vol. 31, p. 1780, (1963).

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