16.alpha.-methyl-17.alpha. 20-epoxysteroid and process

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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514172, C07J 7100, A61F 3158

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active

048914266

ABSTRACT:
C.sub.16 -unsaturated corticoids are readily transformed to the corresponding 16.alpha.-methyl-17.alpha.-hydroxy corticoids by use of a .DELTA.17(20)-20-silyl ether.

REFERENCES:
patent: 2864834 (1958-12-01), Mendelsohn et al.
patent: 3072686 (1963-01-01), Wettstein et al.
patent: 3210341 (1965-10-01), Lincoln et al.
patent: 3231568 (1966-01-01), Julian et al.
patent: 3513163 (1970-05-01), Brown
patent: 3700660 (1972-10-01), Hempel et al.
patent: 3839369 (1974-10-01), Hofmeister et al.
patent: 3876633 (1975-04-01), Loken
patent: 4031080 (1977-06-01), Palladino
patent: 4036831 (1977-07-01), Loken et al.
patent: 4277409 (1981-07-01), Warnant
patent: 4704455 (1987-11-01), Van Rheenen et al.
Organic Reactions in Steriod Chemistry, vol. II, J. Fried and J. A. Edwards, Van Nostrand Reinhold Co., NY (1972), pp. 75-76.
J. Am. Chem. Soc. 80, pp. 3160-3161 (1958).
J. Am. Chem. Soc. 80, p. 4428 (1958).
E. J. Corey in Tetrahedron Letters 26, p. 6019 (1985).
A. Alexakis in Tetrahedron Letters 27, p. 1047 (1986).

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