17-Substituted estradienes and estratrienes

Details 17-Substituted estradienes and estratrienes 17-Substituted estradienes and estratrienes

1987-07-02

1990-01-02

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514175, 514178, 514179, 540 15, 540 28, 540 41, 2603974, 26039745, A61K 3158, A61K 31585, A61K 3156, C07J 100

Patent

active

048913650

ABSTRACT:
17-Substituted estradienes and estratrienes of Formula I ##STR1## wherein ##STR2## R is alkyl, alkenyl or cycloalkyl of up to 5 carbon atoms if ##STR3## R is hydrogen, alkyl, alkenyl or cycloalkyl of up to 5 carbon atoms if ##STR4## is a CC-single or CC-double bond, exhibit, an aldosterone-antagonistic activity and a strong gestagen potency.

REFERENCES:
patent: 4536401 (1985-08-01), Neef et al.
patent: 4540686 (1985-09-01), Philibert et al.

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