Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Alkali or alkaline earth chloride
Patent
1995-04-18
1997-05-13
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Alkali or alkaline earth chloride
424678, 424681, 424682, 424686, 424717, 514 23, 514557, 514561, A61K 31195, A61K 3170, A61K 3310, A61K 3314
Patent
active
056290250
ABSTRACT:
An improved peritoneal dialysis solution comprising an osmotic agent having at least one amino acid, and a method of administering same to a patient are provided. Pursuant to the present invention, the sodium concentration in the solution is decreased thus causing sodium to be transported from the circulation to the peritoneal cavity. This provides for an improved ultrafiltration profile that is, more volume over a longer period of time, for the same initial osmolality when compared to standard solutions. Also, the same ultrafiltration profile as standard solutions can be achieved with lower initial osmolalities.
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Henderson Lee W.
Martis Leo
Moran John
Nakayama Masaaki
Shockley Ty R.
Barrett Robert M.
Baxter International Inc.
Borecki Thomas S.
Mattenson Charles R.
Spivack Phyllis G.
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