Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations
Patent
1995-06-06
1997-05-13
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Topical sun or radiation screening, or tanning preparations
514454, 514455, A61K 742, A61K 740, A61K 3135
Patent
active
056289871
ABSTRACT:
A composition for increasing synthesis of melanin in a human melanocyte thereby enhancing pigmentation of the human skin. Use of this composition promotes tanning of the human skin and increases photoprotection from ultraviolet radiation. An organ culture system comprising viable human foreskin samples which may be used to test the effects of agents on human skin, including pigmentation enhancers on human skin.
REFERENCES:
patent: 2418695 (1947-04-01), Brown
patent: 5075102 (1991-12-01), Hubaud et al.
Sagarin, Cosmetics Science and Technologies, 1957, pp. 189-200.
Kitano, Yukio, "Effects of Dibutyryl Adenosine 3',5'-Cyclic Monophosphate on Human Melanocytes in Vitro", Acta Dermatovener (Stockholm), 56: 223-228 (1976).
Kitano, Yukio, "Effects of Melanocyte Stimulating Hormone Theophylline on Human Melanocytes in Vitro", Arch. Derm. Res., 255: 163-168 (1976).
Fuller et al., "Decay of Hormone Responsiveness in Mouse Melanoma Cells in Culture as a Function of Cell Density", Journal of Cellular Physiology, 103: 279-287 (1980).
Borovicka et al., "Skin protecting preparation against UV radiation", Chemical Abstracts, vol. 92, No. 12, Mar. 12, 1980, Columbus, Ohio, U.S.; Abstract No. 99450.
Fuller et al., "Endocrine Responsiveness in Human Melanocytes and Melanoma Cells in Culture", JNCI, 66(5): 799-802 (1981).
Sheridan et al., "Tritiated-Thymidine-Induced Increased DNA Content and Irreversible Differentiation in a Human Melanoma Cell Line", Br. J. Exp. Path., 62: 289-295 (1981).
Hadley et al., "Topical Application of a Melanotropic Peptide Induces Systemic Follicular Melanogenesis", Life Sciences, 40: 1889-1895 (1987).
Some commercial sun-tanning products which contain tyrosine are "Tan Magnifier" and Tropical Blend by Schering/Plough; Hawaiian Tropic by Tanning Research Labs; Estee Lauder suntan products; and Pre-tanning Accelerator by Tanz.
Dodson Shelley A.
The Board of Regents of the University of Oklahoma
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