Method and apparatus for detecting particular particulate substa

Details Method and apparatus for detecting particular particulate substa Method and apparatus for detecting particular particulate substa

1987-08-10

1990-01-02

Rosenberger, Richard A.

Optics: measuring and testing

For light transmission or absorption

356 36, 356336, 356440, 356442, G01N 2100

Patent

active

048909254

ABSTRACT:
By use of an excitation beam having a wavelength which is equal to, or close to, the sizes of particular particulate substances as the object of analysis, the particulate substances such as an immunoreaction product between an antigen and an antibody or between the antigen and a material supporting the antibody thereon are detected selectively. Very small particles having specific sizes such as rheumatuid factors, cancer specific antigens can be detected with high sensitivity.

REFERENCES:
patent: 4747685 (1988-05-01), Suzuki
Tam et al.: "Measurement of Small Absorptions in Liquids", Optics Letters, vol. 4, No. 3 (Mar. 1979), pp. 81-83.
Oda et al, "Simultaneous Determination of Mixtures in Liquid by Laser-Induced Photoacoustic Spectroscopy", Analytical Chemistry, vol. 51, No. 6 (May 1979), pp. 686-688.
Sawada et al, "Laser-Induced Photoacoustic Spectroscopy of Some Rare Earth Ions on Aqueous Solutions", Analytical Chemistry, vol. 51, No. 6 (May 1979), pp. 688-690.

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