Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-01-04
1995-12-05
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548439, A61K 3140, C07D20988
Patent
active
054729750
ABSTRACT:
There are disclosed various compounds of the formula below, ##STR1## where n, X and R.sub.1 through R.sub.4 are as defined in the specification, which are useful for alleviating various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease.
Compounds of this invention also inhibit monoamine oxidase and/or act at central .alpha..sub.2 -adrenergic receptors, and hence are useful as antidepressants.
REFERENCES:
patent: 3592824 (1971-07-01), Schut
Merriman Michael C.
O'Malley Gerard J.
Ong Helen H.
Palermo Mark G.
Hoechst-Roussel Pharmaceuticals Incorporated
Maurer Barabara V.
Ramsuer Robert W.
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