Method for producing gamma-globulin for use in intravenous admin

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424101, 424176, 424177, C07G 700

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active

043747639

ABSTRACT:
A method for producing gamma-globulin in its native state derived from human sources and suitable for use in intravenous administration and having an anti-complementary activity of lower than 20% (C'H.sub.50 v) is disclosed, in which raw human gamma globulin is brought into suspension in an aqueous solution of a monosaccharide, disaccharide or sugar alcohol, adjusted to a pH value of 7.0 to 9.0 and then subjected to fractional precipitation by adding dextran thereto. The fractions showing anti-complementary activity are removed as precipitates.

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Acta Chemica Scandinavica 24, (1970), pp. 1585-1589.

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