Heteroatom substituted benzoyl derivatives that enhance synaptic

Details Heteroatom substituted benzoyl derivatives that enhance synaptic Heteroatom substituted benzoyl derivatives that enhance synaptic

1995-06-05

1999-04-06

Gupta, Yogendra N.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514212, 540607, 544130, 544152, A61K 31535, C07D41304

Patent

active

058918760

ABSTRACT:
Compounds useful for enhancing synaptic responses mediated by AMPA receptors are disclosed, as are methods for the preparation thereof, and methods for their use for treatment of subjects suffering from impaired nervous or intellectual functioning due to deficiencies in the number of excitatory synapses or in the number of AMPA receptors. The invention compounds can also he used for the treatment of non-impaired subjects for enhancing performance in sensory-motor and cognitive tasks which depend on brain networks utilizing AMPA receptors and for improving memory encoding.

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