Prolonged release therapeutic compositions based on hydroxypropy

Details Prolonged release therapeutic compositions based on hydroxypropy Prolonged release therapeutic compositions based on hydroxypropy

1981-12-18

1983-01-18

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 22, 424362, A61K 902, A61K 920, A61K 922, A61K 926

Patent

active

043691722

ABSTRACT:
A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being hydroxypropylmethylcellulose or a mixture of hydroxypropylmethylcellulose and up to 30% by weight of the mixture of ethylcellulose and/or up to 30% by weight of the mixture of sodium carboxymethylcellulose, and wherein the hydroxypropylmethylcellulose has a hydroxypropoxyl content of 9-12 weight % and a number average molecular weight of less than 50,000.

REFERENCES:
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patent: 3065143 (1962-11-01), Christenson et al.
patent: 3839319 (1974-10-01), Greminger et al.
patent: 3852421 (1974-12-01), Koyanagi et al.
patent: 3870790 (1975-03-01), Lowey et al.
patent: 4091205 (1978-05-01), Onda et al.
patent: 4167558 (1979-09-01), Sheth et al.
patent: 4226849 (1980-10-01), Schor
patent: 4259314 (1981-03-01), Lowey
patent: 4265875 (1981-05-01), Byrne et al.
patent: 4292299 (1981-09-01), Suzuki et al.

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