Substituted-hetero-cyclopentanones and cyclopentenones and deriv

Details Substituted-hetero-cyclopentanones and cyclopentenones and deriv Substituted-hetero-cyclopentanones and cyclopentenones and deriv

1990-05-21

1991-11-19

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514252, 514256, 514275, 514304, 514305, 514314, 514340, 514342, 514343, 514365, 514374, 514394, 514397, 514406, 514415, 544238, 544323, 544335, 544336, 546125, 546135, 546152, 546209, 546283, 546284, 546280, 546281, 548204, 548235, 548327, A61K 3144, C07D40502

Patent

active

050666630

ABSTRACT:
Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting muscarinic agents and are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.

REFERENCES:
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patent: 4970217 (1990-11-01), Prucher et al.
Gonzales et al. Tetra Hedron Letters, vol. 30, No. 16 pp. 2145-2148 (1984).
Sauerberg et al. Chem. Abstr. vol. 110 Entry 231941p, (1989).

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