Chromanol glycoside and method for production thereof

Details Chromanol glycoside and method for production thereof Chromanol glycoside and method for production thereof

1994-02-10

1995-12-26

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514451, 536 41, 536120, A61K 3170, A61K 3135, C07H 1520, C07H 1504

Patent

active

054788129

ABSTRACT:
This invention provides a novel chromanol glycoside which is a water soluble antioxidant excellent in heat and pH stability and production method thereof. It is a chromanol glycoside represented by the general formula (1): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 independently are a hydrogen atom or a lower alkyl group, R.sup.5 is a hydrogen atom, a lower alkyl group, or a lower acyl group, X is a monosaccharide residue or an oligosaccharide residue, providing the hydrogen atom of the hydroxyl group of saccharide residue may be substituted by a lower alkyl group or a lower acyl group, n is an integer in the range of 0 to 4, and m is an integer in the range of 1 to 6.

REFERENCES:
Yoshioka, T. et al., "Studies on Hindered Phenols and Analogues. V. Synthesis, Identification . . . ", Chem. Pharm. Bull. 39(8) (1991) pp. 2124-2125.
JACS vol. 109 No. 2 (1987) Harada et al. pp. 527-532.

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