Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1997-05-12
1999-04-06
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
128831, 128832, 128833, 604 55, 604 56, A61F 606, A61M 3100
Patent
active
058914579
ABSTRACT:
A method and composition for effecting chemical necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by delivering a caustic tissue necrosing composition, e.g., a silver nitrate and dextran paste, to the tissue to be necrosed and allowing the paste to remain in contact with the target tissue for a period of time sufficient to chemically necrose substantially the entirety of the tissue lining, and then contacting the caustic composition with a deactivating agent, e.g., an aqueous sodium chloride solution, thereby rendering the caustic composition non-caustic, and then rinsing the cavity. Compositions and methods for delivering medicaments are also disclosed.
REFERENCES:
patent: 1652954 (1927-12-01), Pierce
patent: 2190384 (1940-02-01), Newman
patent: 2355231 (1944-08-01), Moore
patent: 3174481 (1965-03-01), Seaman
patent: 3394705 (1968-07-01), Abramson
patent: 3459175 (1969-08-01), Miller
patent: 3540451 (1970-11-01), Zemma
patent: 3803308 (1974-04-01), Zipper et al.
patent: 3817248 (1974-06-01), Buckles et al.
patent: 3822702 (1974-07-01), Bolduc
patent: 3848602 (1974-11-01), Gutnick
patent: 3875939 (1975-04-01), Bolduc et al.
patent: 3887112 (1975-06-01), Bolduc et al.
patent: 3924628 (1975-12-01), Droegemueller et al.
patent: 3948259 (1976-04-01), Bolduc et al.
patent: 3964477 (1976-06-01), Ellis et al.
patent: 3972331 (1976-08-01), Bolduc et al.
patent: 4012839 (1977-03-01), Hill
patent: 4071027 (1978-01-01), Meador
patent: 4109654 (1978-08-01), Bolduc et al.
patent: 4119098 (1978-10-01), Bolduc et al.
patent: 4126134 (1978-11-01), Bolduc et al.
patent: 4137922 (1979-02-01), Leininger et al.
patent: 4160446 (1979-07-01), Barrington
patent: 4293536 (1981-10-01), Jensen et al.
patent: 4430076 (1984-02-01), Harris
patent: 4585438 (1986-04-01), Makler
patent: 4601698 (1986-07-01), Moulding, Jr.
patent: 4637818 (1987-01-01), Johnson et al.
patent: 4773899 (1988-09-01), Spears
patent: 4857555 (1989-08-01), Smith et al.
patent: 4863932 (1989-09-01), Sinensky et al.
patent: 4891043 (1990-01-01), Zeimer et al.
patent: 5030202 (1991-07-01), Harris
patent: 5039704 (1991-08-01), Smith et al.
patent: 5063065 (1991-11-01), Bazterrica et al.
patent: 5100388 (1992-03-01), Behl et al.
patent: 5104377 (1992-04-01), Levine
patent: 5105808 (1992-04-01), Neuwirth et al.
patent: 5163905 (1992-11-01), Michael
patent: 5170774 (1992-12-01), Heckele
patent: 5174304 (1992-12-01), Latina et al.
patent: 5188602 (1993-02-01), Nichols
patent: 5192688 (1993-03-01), Switzer, III et al.
patent: 5195965 (1993-03-01), Shantha
patent: 5242390 (1993-09-01), Goldrath
patent: 5242437 (1993-09-01), Everett et al.
patent: 5256139 (1993-10-01), Ghodsian
patent: 5257977 (1993-11-01), Eshel
patent: 5279542 (1994-01-01), Wilk
patent: 5282785 (1994-02-01), Shapland et al.
patent: 5286254 (1994-02-01), Shapland et al.
patent: 5290763 (1994-03-01), Poser et al.
patent: 5298018 (1994-03-01), Narcisco, Jr.
patent: 5300023 (1994-04-01), Lowery et al.
patent: 5304214 (1994-04-01), DeFord et al.
patent: 5306249 (1994-04-01), Michel
patent: 5364375 (1994-11-01), Swor
patent: 5371191 (1994-12-01), Poser et al.
patent: 5372584 (1994-12-01), Zink et al.
patent: 5380317 (1995-01-01), Everett et al.
patent: 5397803 (1995-03-01), Smith et al.
patent: 5403309 (1995-04-01), Coleman et al.
patent: 5403311 (1995-04-01), Abele et al.
patent: 5423807 (1995-06-01), Milder
patent: 5431662 (1995-07-01), Nicholas
patent: 5433708 (1995-07-01), Nichols et al.
patent: 5434247 (1995-07-01), Jones
patent: 5435805 (1995-07-01), Edwards et al.
patent: 5437660 (1995-08-01), Johnson et al.
patent: 5445961 (1995-08-01), Genovesi et al.
patent: 5451208 (1995-09-01), Goldrath
patent: 5453086 (1995-09-01), Weber
Nechay et al., "Inhibition of Adenosine Triphosphates In Vitro By Silver Nitrate Silver Sulfadiazine", Journal of Environmental Pathology, Toxicology, and Oncology, vol. 5, No. 4-5, pp. 119-126 (1984).
Nechay et al., "Inhibition of Adenosine Triphosphatases In Vitro By Silver Nitrate And Silver Sulfadiazine", Journal of the American College of Toxicology, vol. 3, No. 1, pp. 37-42 (1984).
Williams et al., "Chemical Injury of Arteries", Journal of Pathology and Bacteriology, vol. 77, pp. 63-69 (1959).
No author, Silver nitrate wart treatment available OTC; Launches Avoca, a silver nitrate pencil for wart removal, Chemist & Druggist, 1994 Jul. 16, p. 38 (1994).
No author, "Novel Biocide Design Using an Inorganic Composite", Speciality Chemicals, 1994 Jun., p. 223 (1994).
No author, "Spectrum Chemical and Safety Products", pp. S-xii, C-392-C-393 (1993-1994).
Richart et al., "Single-application fertility-regulating device: Description of a new instrument", Obstet. Gynecol. 127:86, 1977.
Paul et al., "Transvaginal Human Sterilization: A Preliminary Report", ASC Symposium Series 33, American Chemical Society, Washington, D.C., 1976.
Gregor et al., "Fallopian Tube Cauterization by Silver Ion-Polymer Gels", Controlled Release Polymeric Formulations, pp. 147-156.
Thompson et al., "Evaluation of Experimental Methods of Occluding the Uterotubal Junction", Female Sterilization (Prognosis for Simplified Outpatient Procedures), Academic Press, 1972, pp. 107-123.
Martens, F., "Attempted Cyrosurgical Closure of the Fallopian Tubes", Human Sterilization (A Conference), Charter 26, pp. 305-312, Charles C. Thomas, Springfield, Ill.
Stevenson et al., "The Effect of Methyl Cyanoacrylate Tissue Adhesive on the Human Fallopian Tube and Endometrium," The Journal of Obstetrics and Gynaecology of the British Commonwealth, Nov. 1972, vol. 79, pp. 1028-1039.
Mullick et al., "Studies of Quinacrine and of Tetracycline for Non-surgical Female Sterilization", Indian Rural Medical Association, Adv Contracept (England), Sep. 1987, pp. 245-254.
Benoit et al., "Chemically Induced Tubal Occlusion in the Human Female Using Intrauterine Instillation of Quinacrine", Contraception (United States), Jul. 1975, pp. 95-101.
Bhatt et al., "Four Year Follow Up of Insertion of Quinacrine Hydrochloride Pellets as a Means of Nonsurgical Female Sterilization", Fertil Steril (United States), Sep. 1985, pp. 303-306.
Chandra, "Toxic Effects of Quinacrine Hydrochloride in Rhesus Monkeys", Contraception (United States), Sep. 1981. pp. 269-274.
Ciaccio et al., "Observation on Toxic Effects of Quinacrine Hydrochloride (in rodents)", Contraception (United States), Mar. 1978, pp. 231-236.
Dubin et al., "Effect of Intrauterine Administration of Tetracyclines on Cynomolgus Monkeys", Contraception (United States), Jun. 1984, pp. 561-571.
Dubin et al., "Comparative Effects of Intrauterine Instillation of Analogues of Quinacrine and Tetracycline on Uterine Morphology in the Rat", Contraception (United States), Jun. 1984, pp. 553-559.
Dubin et al., "Effect of Intrauterine and Intravascular Quinacrine Administration of Histopathology, Blood Chemistry, and Hematology in Cynomolgus Monkeys", Fertil Steril (United States), Dec. 1982, pp. 741-747.
Dubin et al., "Pharmacokinetic Studies on Quinacrine Following Intrauterine Administration to Cynomolgus Monkeys", Fertil Steril (United States), Dec. 1982, pp. 735-740.
el-Kady, et al., "Histopathologic Changes in the Cornual Portion of the Fallopian Tube Following a Single Transcervical Insertion of Quinacrine Hydrochloride Pellets", Department of Obstetrics and Gynecology, Boulak El-Dakrour Hospital, Giza, Egypt.
Laufe et al., "Nonsurgical Female Sterilization", Int J Gynaecol Obstet (United States), 1980, pp. 334-339.
Merchant et al., "Clinicopathologic Study of Fallopian Tube Closure After Single Transcervial Insertion of Quinacrine Pellets", Obstetrics and Gynecology, B.Y.L. Nair Hospital, Bombay, India, Int J Fertil Menopausal Stud (United States), Jan.-Feb. 1995, pp. 47-54.
Mukherjee et al., "Fluorescence of X and Y Chromatin in Human Interphase Cells", Cytogenetics (Switzerland), 1972, pp. 216-227.
Patek, "Quinacrine Hydrochloride. Review and Mode of Action of an Antimalarial, Used as an Occlusive Agent for Transvaginal Human Sterilzation", Acta Obstet Gynecol Scand (Sweden), 1979, pp. 561-564.
Pollack et al., "Association for
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