Imidazole analogs of mevalonolactone and derivatives thereof for

Details Imidazole analogs of mevalonolactone and derivatives thereof for Imidazole analogs of mevalonolactone and derivatives thereof for

1987-11-20

1989-02-28

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514397, 548336, 548342, 548343, A61K 31415, C07D23364

Patent

active

048086070

ABSTRACT:
Compounds of the formula ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein the various substituents are defined hereinbelow and the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

REFERENCES:
patent: 4530922 (1985-07-01), Moberg

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