Process for the preparation of substituted indoles

Details Process for the preparation of substituted indoles Process for the preparation of substituted indoles

1994-02-10

1994-10-25

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548490, 558260, C07D20904, C07C 6996

Patent

active

053590830

ABSTRACT:
The invention relates to a novel process for the preparation of compounds of formula I ##STR1## wherein R is straight-chain C.sub.2 -C.sub.4 alk-1-en-1-yl, and salts thereof, and to a novel starting material and the use thereof.

REFERENCES:
patent: 4837235 (1989-06-01), Bernstein et al.
patent: 4859692 (1989-08-01), Bernstein et al.
patent: 4918094 (1990-04-01), Bernstein et al.
patent: 5096917 (1992-03-01), Sallman
Matassa, et al.; "Evolution of a Series of Peptidoleukotriene Antagonists: Synthesis and Structure/Activity Relations of 1,3,5-Substituted Indoles and Indazoles", J. Med. Chem. 1990, 33, 1781-1790.
Chemical Abstracts, vol. 100, abstract 210430.sub.2, Pozdnev, V. F., SU 1,077,881, 1984.

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