Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-07-12
1995-12-12
Warden, Jill
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 530399, 530300, 530350, 514970, A61K 3700
Patent
active
054749824
ABSTRACT:
Proteins having substantially the same biological activity as PDGF are provided. In one aspect, a protein homodimer having two polypeptide chains is disclosed, each of the chains being a mosaic of amino acid sequences substantially identical to portions of the A- and B-chains of PDGF, the protein being chemotactic or mitogenic for fibroblasts. Therapeutic compositions comprising such proteins in combination with a physiologically acceptable carrier or diluent are also provided. Such therapeutic compositions may be used within methods for enhancing the wound-healing process in warm-blooded animals.
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patent: 4874746 (1989-10-01), Antoniades et al.
patent: 5128321 (1992-07-01), Murray
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Kelly James D.
Murray Mark J.
Prickril Benet
Warden Jill
ZymoGenetics Inc.
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