Substituted keto and alkoxy 16-phenoxy and 17-phenyl PGE.sub.2 -

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260473A, C07C 6976, C09B 1110

Patent

active

040101720

ABSTRACT:
Substituted phenyl and naphthyl esters of PGE.sub.2 analogs, including the 16-alkyl, 16-fluoro, 16-phenoxy, and phenyl-substituted analogs, and their 15-epimers, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as these PGE.sub.2 analogs, and are also useful as a means for obtaining highly purified 16,16-dimethyl-PGE.sub.2, 16-phenoxy-17,18,19,20-tetranor-PGE.sub.2, and 17-phenyl-18,19,20-trinor-PGE.sub.2.

REFERENCES:
patent: 3894062 (1975-07-01), Morozowich

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