Cough/cold mixtures comprising non-steroidal anti-inflammatory d

Details Cough/cold mixtures comprising non-steroidal anti-inflammatory d Cough/cold mixtures comprising non-steroidal anti-inflammatory d

1985-07-08

1986-10-28

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514290, 514325, 514568, A61K 3119, A61K 3144, A61K 31435, A61K 31445

Patent

active

046199349

ABSTRACT:
Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.

REFERENCES:
patent: 4115589 (1978-09-01), Lednicer
patent: 4226848 (1980-10-01), Nagai et al.
patent: 4374836 (1983-02-01), Yellin et al.
patent: 4447443 (1984-05-01), Goldenberg
Vargaftig et al., "Non-Steroidal Anti-Inflammatory Drugs if Combined with Anti-Histamine and Anti-Serotonin Agents Interfere with the Bronchial and Platelet Effects of `Platelet-Activating Factor` (PAF-Acether)," European Journal of Pharmacology, 82, pp. 121-130 (1982).
Kordansky et al., "Asthma Improved by Nonsteroidal Anti-Inflammatory Drugs", Annals of Internal Medicine, 88, pp. 508-511 (1978).
Abstract, Kumar et al., "Are Non-Steroidal Anti-Inflammatory Agents Beneficial in the Treatment of Allergic Rhinitis".
Fairfax et al., "NSAIDs Inhibit the Late Asthmatic Response to Antigen Challenge", Proceedings of the B.P.S., pp. 984P-985P, 16th-18th Sep. 1981.
Brooks et al., "Effect of Flurbiprofen, a Cyclooxygenase Inhibiting Drug, on Induced Allergic Rhinitis", J. Allergy Clin. Immunol., 73, No. 5, Part 1, pp. 584-589 (May 1984).

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