26,26,26,27,27-pentafluoro-1.alpha.-hydroxy-27-methoxyvitamin D.

Details 26,26,26,27,27-pentafluoro-1.alpha.-hydroxy-27-methoxyvitamin D. 26,26,26,27,27-pentafluoro-1.alpha.-hydroxy-27-methoxyvitamin D.

1985-09-16

1986-10-28

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

2603972, C07J 900

Patent

active

046199209

ABSTRACT:
The invention provides a new derivative of vitamin D.sub.3, 26,26,26,27,27-pentafluoro-1.alpha.-hydroxy-27-methoxy-cholecalciferol and a process for preparing the same.
The compound is characterized by some vitamin D-like activity except that it exhibits negligible activity in mobilizing bone. This characteristic indicates that the compound would find ready application in the treatment of disease or physiological states which evince loss of bone mass and application in other situations where metabolic calcium imbalances are found.

REFERENCES:
patent: 4358406 (1982-11-01), DeLuca et al.
patent: 4411833 (1983-10-01), DeLuca et al.

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