Production of muconic acid

Details Production of muconic acid Production of muconic acid

1981-07-27

1982-10-19

Penland, R. B.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435253, 435877, C12P 744

Patent

active

043551076

ABSTRACT:
This invention provides a process for microbiological oxidation of toluene to muconic acid.
The toluene oxidation is achieved with novel strains of microorganisms (e.g., Pseudomonas putida Biotype A) which are capable of converting toluene to muconic acid quantitatively by the ortho (.beta.-ketoadipate) pathway.
Munonate lactonizing enzyme is not induced in the microorganism, thereby permitting the muconic acid to be produced and accumulated in a quantity greater than one gram of muconic acid per liter of conversion medium.

REFERENCES:
patent: 3383289 (1968-05-01), Raymond et al.
patent: 3419469 (1968-12-01), Humphrey et al.

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