Process for preparing optically active 2-hydroxy-methyl-3-phenyl

Details Process for preparing optically active 2-hydroxy-methyl-3-phenyl Process for preparing optically active 2-hydroxy-methyl-3-phenyl

1999-11-30

2000-07-25

Geist, Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562402, C07B 5700

Patent

active

060938463

ABSTRACT:
A process for preparing optically active 2-hydroxymethyl-3-phenylpropionic acid by resolving (RS)-2-hydroxymethyl-3-phenylpropionic acid via crystallization of an optically active amine salt, where the amine is optically active cis-1-amino-2-indanol salt, optically active .alpha.-methylbenzylamine salt, or optically active 3-methyl-2-phenyl-1-butylamine salt.

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