Nicotinamide derivative, process for preparing the same and phar

Details Nicotinamide derivative, process for preparing the same and phar Nicotinamide derivative, process for preparing the same and phar

1980-11-17

1982-12-28

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546262, C07D21356, A61K 31455

Patent

active

043661610

ABSTRACT:
Novel compound, 1,2-bis(nicotinamido)propane and its pharmaceutically acceptable salts, a process for preparing the same and a pharmaceutical composition containing the same as an active ingredient are disclosed.
The compound acts to prevent or spasmolyse cerebral vasospasms, to prevent cerebral apoplexy and to lower the lipoperoxide level in blood.

REFERENCES:
patent: 3786058 (1974-01-01), Edwards
patent: 3875174 (1975-04-01), Edwards
C.A., 94:139627u, Chugai (1980).
C.A., 59, Grudzinski et al., 7476f (1963).
C.A. 67, Ojima et al., 7591k (1967).
Weygand et al., "Preparative Organic Chemistry", 1972, John Wiley & Sons, N.Y., pp. 464-467, 484-485, 488-489.

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