Substituted bicyclic heteroaroylguanidines, a process for their

Details Substituted bicyclic heteroaroylguanidines, a process for their Substituted bicyclic heteroaroylguanidines, a process for their

1998-11-18

2000-07-25

Davis, Zinna Northington

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514311, 546139, 546146, 546152, 546156, C07D21500, C07D21700, A61K 3147

Patent

active

060937297

ABSTRACT:
Substituted bicyclic heteroaroylguanidines, a process for their preparation, their use as a medicament or a diagnostic agent, and a medicament containing them are described, as are the pharmaceutically tolerated salts thereof. A process for their preparation, and their use as medicines and diagnostic aids in cardiovascular diseases, is also described.

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H. Lorne Davis et al., "2,3-Disubstituted 1,8-Naphthyridines as Potential Diuetic Agents. 3. 4- and 7-Phenyl Derivatives," Eur. . Med. Chem.--Chim. Ther., vol. 20, No. 4, pp. 381-383, 1985.
E.M. Hawes et al., "2-3-Disubstituted 1,8-Naphthyridines as Potential Diuretic Agents. 2. 5,7-Dimethyl Derivatives," J. Med. Chem. (JCMAR), 77, vol. 20, No. 6, pp. 838-841, 1977.
D.K.J. Gorecki et al., "2,3-Disubstituted 1,8-Naphthyridines as Potential Diuretic Agents," J. Med. Chem. (JCMAR), 77, vol. 20, No. 1, pp. 124-128, 1977.
E.M. Hawes et al., "2,3-Disubstituted 1,6-Naphthyridines as Potential Diuretic Agents," J. Med. Chem. (JCMAR), 73, vol. 16, No. 7, pp. 849-853, 1973.
Davis et al., Chemical Abstracts, vol. 105, N. 7, Abstract No. 60552C, p. 611, Aug. 18, 1986.

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