Intermediates and processes for .beta.-6-hydroxymethyl HMG-CoA r

Details Intermediates and processes for .beta.-6-hydroxymethyl HMG-CoA r Intermediates and processes for .beta.-6-hydroxymethyl HMG-CoA r

1988-02-29

1990-01-16

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549214, 544 59, 544 60, 544149, 544359, 544389, 546207, 546245, 548518, 548531, C07D30930

Patent

active

048944661

ABSTRACT:
This invention discloses intermediates and a process for the preparation of 6-desmethyl-6-.beta.-hydroxymethyl derivatives of lovastatin and analogs thereof at the 8-acyl side chain.

REFERENCES:
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4582915 (1986-04-01), Sletienger et al.
Hesse, Adv. Free Rad. Chem., 3, 83-137 (1969).
D. H. R. Barton, Pure Appl. Chem., 16, 1-15 (1968).
Akhtar, Adv. Photochem, 2, 263-304 (1964).

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