Direct compression tablet binders for acetaminophen

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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Details

424476, 424502, A61K 926

Patent

active

048942367

ABSTRACT:
Dry, directly compressed tablets are provided by a blend of from 60 to 90 weight percent of acetaminophen and from 10 to 40 weight percent of non-ionizable lipid having a melting point of from 55.degree. C. to 80.degree. C. The preferred lipid is hydrogenated cotton seed oil. The tablets are characterized by a hardness of at least 5 kgs. When produced by a conventional tabletting machine using a pressure of 1.5 to 20 tons per square inch.

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"Problem Solver" A reference manual by FMC Corp. p. IV-A-11.

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