Fused benzeneoxyacetic acid derivatives

Details Fused benzeneoxyacetic acid derivatives Fused benzeneoxyacetic acid derivatives

1992-11-05

1994-09-06

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514357, 514428, 514534, 514563, 546265, 546336, 548561, 560 42, 562451, 562457, A61K 3144, C07D21302

Patent

active

053448367

ABSTRACT:
A fused benzenoxyacetic acid derivative of the formula (I): ##STR1## and salts thereof possess an agonistic on PGI.sub.2 receptor, so it is useful for prevention and/or treatment of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer and hypertention.

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Nature, vol. 263, Oct. 21, 1976, pp. 663-665.
Prostaglandins, vol. 12, No. 5, Nov. 1976, pp. 685-713.
Prostaglandins, vol. 12, No. 6, Dec. 1976, pp. 915-928.
Prostaglandins, vol. 13, No. 3, Mar. 1977, pp. 375-388.
Chemical & Engineering News, Dec. 20, 1976, pp. 17-19.
Br. J. Pharmac. 76, 1982, pp. 423-438.
Br. J. Pharmac. 84, 1985, pp. 595-607.
Br. J. Pharmac. 102, 1991, pp. 251-265.

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