Methods useful in endotoxin prophylaxis and therapy

Details Methods useful in endotoxin prophylaxis and therapy Methods useful in endotoxin prophylaxis and therapy

1992-08-12

1994-09-06

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 12, A61K 3702, C07K 708

Patent

active

053448227

ABSTRACT:
Treatment and prophylaxis of endotoxin caused toxicity is disclosed. This is accomplished by administering a lipid into which the endotoxin of concern is associated, preferably together with a peptide which is not an apolipoprotein. Preferably, the two components are administered in the form of a reconstituted particle, although this is by no means required.

REFERENCES:
patent: 5128318 (1992-07-01), Levine
Anantharamiah, "Methods in Enzymology", vol. 128, pp. 627-647 (1986).

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