Preparation of 2-amino-7-(1-substituted-2-hydroxyethyl)-3, 5-dih

Details Preparation of 2-amino-7-(1-substituted-2-hydroxyethyl)-3, 5-dih Preparation of 2-amino-7-(1-substituted-2-hydroxyethyl)-3, 5-dih

1998-05-28

2000-03-28

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544238, C07D48704

Patent

active

060433655

ABSTRACT:
The compounds of formula I ##STR1## wherein Ar represents biaryl, carbocyclic or heterocyclic aryl, are prepared, as substantially pure enantiomers, by

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Ealick, et al., Proc. Natl. Acad. Sci., vol. 88, pp. 11540-11544 (1991).
Erion, et al., J. Med. Chem., vol. 36, pp. 3771-3783 (1993).
Lim, et al., J. Org. Chem., vol. 44, No. 22, pp. 3826-3829 (1979).
Lim et al., J. Org. Chem., vol. 48, pp. 780-788 (1983).

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