Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1997-10-10
2000-03-28
Park, Hankyel
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
435 5, 530324, 530325, 530326, 5303894, C07K 1600, C12Q 170, A61K 3800
Patent
active
060433477
ABSTRACT:
Methods and compositions for treatment, diagnosis, and prevention of a virus comprise administering to a patient antibodies which react with regions of viral proteins and result in neutralization of infectivity and inactivation of functionally essential events in the life cycle of the virus. The antibodies recognize viral epitopes which fail to elicit an immune response in man when encountered through infection or naturally through the environment. In a preferred embodiment, the invention provides compositions and methods useful in the treatment and diagnosis of human immunodeficiency virus (HIV) infections.
REFERENCES:
patent: 5156949 (1992-10-01), Luciw et al.
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Kent et al., Identification of Two Neutralizing and 8 Non-Neutralizing Epitopes on Simian Immunodeficiency Virus Envelope Using Monoclonal Antibodies, AIDS Res. Hum. Retroviruses 8:1147-1151, see Abstract, last sentence, 1992.
Kusk et al., AIDS Res. Human Retro., 1992, vol. 8, No. 10, pp. 1789-1794.
Laman et al., AIDS Res. Human Retro., 1993, vol. 9, No. 7, pp. 605-612.
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Ehrhard et al., Biochemistry, 1996, vol. 35, No. 28, pp. 9097-9105.
Bou et al., AIDSLINE, AN 95:13321, 1995.
Shi et al., AIDSLINE, AN 93:10991, 1993.
Park Hankyel
Probe International Inc.
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