Nucleic acids encoding novel human serine/threonine protein kina

Details Nucleic acids encoding novel human serine/threonine protein kina Nucleic acids encoding novel human serine/threonine protein kina

1996-11-15

1999-11-16

Teng, Sally P.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435 691, 4352523, 43525411, 4353201, 435325, 536 232, 536 2431, C12N 1554, C12N 912

Patent

active

059856351

ABSTRACT:
The present invention provides human serine/threonine kinase (HSTK) and polynucleotides which identify and encode HSTK. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSTK and a method for producing HSTK. The invention also provides for use of HSTK and agonists, antibodies, or antagonists specifically binding HSTK, in the prevention and treatment of diseases associated with expression of HSTK. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSTK for the treatment of diseases associated with the expression of HSTK. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HSTK.

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