Polynucleotides encoding natural killer cell enhancing factor C

Details Polynucleotides encoding natural killer cell enhancing factor C Polynucleotides encoding natural killer cell enhancing factor C

1995-06-06

1999-11-16

Mertz, Prema

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 701, 435 711, 4352523, 4353201, 435325, 435471, 536 231, 536 235, 530351, C07K 1452, C12N 510, C12N 1519, C12N 1563

Patent

active

059856122

ABSTRACT:
A human natural killer cell enhancing factor C and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for preventing and/or treating viral infections, inflammation, neoplasia and damage from superoxide radicals. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.

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Genbank Accession No. U25182 (May 9, 1995). Jin, D.-Y. et al.
Genseq Accession No. T20740 (Jul. 26, 1996). Matsuhara K. et al.
Genbank Accession No. R27341 (Apr. 24, 1995). Hillier L. et al.
Genbank Accession No. F00772 (Mar. 14, 1995). Auffrey. C. et al.
Genbank Accession No. R27342 (Apr. 24, 1995). Hillier L. et al.
George et al. Macromolecular Sequencing & Synthesis, Selected Methods & Applications. Ch. 12, pp. 127-149, Alan R. Liss, Inc., New York, 1988.
Chae et al. Proc. Natl. Acad. Sci. USA, vol. 91, pp. 7017-7021, 1994.

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