Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-04-02
1999-07-20
Dees, Jose' G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514408, 548566, 548569, 548570, 548571, C07D 2900, C07D29500, C07D29504, A61K 3140
Patent
active
059256672
ABSTRACT:
A pyrrolidine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein R.sub.1 is an alkenyl group; R.sub.2 is a lower alkoxy group or a halogen atom;
REFERENCES:
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D.E. Schmidt et al., Chemical Abstract vol. 120, No. 11 Abstract No. 124115g Aromatic and amine substituent effects on the apparent 1994.
J.K. Desai et al., Chemical Abstract vol. 122, No. 5 Abstract No. 46178e Gastric and duodenal anti-ulcer activity of sulpiride, a dopamine Jan. 30, 1995.
G. Orzalesi et al., Chemical Abstract vol. 85, No. 23 Abstract No. 177207d Some new derivatives of 2-aminomethyl-N-ethylpyrrolidine 3-amino-N-ethylpiperidine with antiemetic and antiulcer activity Dec. 6, 1976.
J. LaBarre: Chemical Abstract vol. 72 No. 1 Abstract No. 2037c Antigastric ulcer and excitomotor effects of sulpiride Jan. 5, 1970.
Schmidt et al. (J. of Pharm. Sci., vol. 83, No. 3, Mar. 1994).
Nishino Chikao
Uetake Tomohiro
Chao Fei-Fei
Dees Jos,e G.
Qazi Sabiha N.
Shiseido Co. Ltd.
Snider Ronald R.
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