Naphthalenylsulfonylimidazolidinediones and their thioxo analogs

Details Naphthalenylsulfonylimidazolidinediones and their thioxo analogs Naphthalenylsulfonylimidazolidinediones and their thioxo analogs

1987-02-09

1988-05-10

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548311, A61K 31415, C07D40330

Patent

active

047436115

ABSTRACT:
Disclosed herein are naphthalenylsulfonylimidazolidinediones and their thioxo analogs and methods for their preparation. The compounds are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

REFERENCES:
I. Miwa, Biochemical Pharmacology, 36, 2789-2794 (1987).
J. Okuda et al., Seventh International Congress of Eye Research, held in Nagoya, Japan, Sep. 25 to Oct. 1, 1986, p. 175. Abstract.

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