Antibacterial 2-(azacycloalkyl) penems

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540310, A61K 3143, C07D49900

Patent

active

047435984

ABSTRACT:
Disclosed are 6-(1'hydroxyethyl)-2-(azacycloalkyl)penem-3-carboxylic acids and salts or metabolizable esters thereof having an absolute stereochemistry of 5R,6S,8R. The compounds are useful and potent antibacterial agents and can be formulated into a variety of forms suitable for oral, parenteral or topical use.

REFERENCES:
patent: 4271172 (1981-06-01), Rodriguez et al.
patent: 4386030 (1983-05-01), Christensen et al.
Miller, G. et al., Clinical Trials Journal, 1980, 17, 6, 244-245.
Derwent Abstract of EP 70204, (published 1/19/83).

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