Nucleic acid sequences encoding human leucine-zipper protein-kin

Details Nucleic acid sequences encoding human leucine-zipper protein-kin Nucleic acid sequences encoding human leucine-zipper protein-kin

1994-03-01

1996-09-10

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

4352523, 4353201, 536 232, C12N 120, C12N 1500, C12N 912

Patent

active

055545238

ABSTRACT:
A novel protein kinase, leucine-zipper protein kinase, 668 amino acids in length is provided by the present invention. This protein kinase is localized to the human brain. Nucleic acid sequences encoding the protein kinase are also provided.

REFERENCES:
Asano et al., "Domains Responsible for the Differntial Targeting of Glucose Transporter Isoforms", J. Biol. Chem. 267: 19636-19641 (1992).
Forman et al., "A Domain Containing Leucine-Zipper-Like Motifs mediate novel In Vivo Interactions Between the Thyroid hormone and Retinoic Acid Receptors", Molecular Endocrinology 3: 1610-1626 (1989).
Pleasure et al., "Pure, Postmitotic, Polarized Human Neurons Derived from NTera 2 Cells Provide a System for Expressing Exogenous Proteins in Terminally Differentiated Neurons", J. Neuroscience 12: 1802-1814 (1992).
Wernet et al., "the cDNA of The Two Isoforms of Bovine cGMP-Dependent Protein Kinase",FEBS251: 191-196 (1989).
Younkin et al., "Inducible Expression of Neuronal Glutamate Receptor Channels in the NT2 Human Cell Line", Proc. Natl. Acad. Sci. USA 90: 2174-2178 (1993).

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