Process for preparing retinoyl chlorides

Details Process for preparing retinoyl chlorides Process for preparing retinoyl chlorides

1986-09-22

1988-05-10

Killos, Paul J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260544L, 564188, 564172, C07C17500

Patent

active

047434007

ABSTRACT:
A process to prepare retinoyl chlorides, e.g., of the following formula (I): ##STR1## under very mild chlorinating conditions by the action of a reagent amount of dimethylchloroformamidinium chloride on a corresponding retinoic acid.

REFERENCES:
patent: 4055659 (1977-10-01), Gander et al.
patent: 4108880 (1978-08-01), Gander et al.
patent: 4190594 (1980-02-01), Gander et al.
patent: 4323581 (1982-04-01), Gander
Chem. Abstracts, vol. 51, #13761c (1957).
Chem. Abstracts, vol. 54, #8618i (1960).
Chem. Abstracts, vol. 53, #4112c (1959).
Chem. Abstracts, vol. 53, #4164a (1959).
"176, Eine Methode zur Katalysierten Herstellung von Carbonsaure- und Salfosaure-Chloriden mit Thionylchorid.sup.1)", Bosshard et al., Fasciculus v, vol. XLII (1959), No. 175-176, pp. 1653-1658.
"N-(4-Hydroxyphenyl)Retinamide, A New Retinoid for Prevention of Breast Cancer in the Rat", Moon et al., Cancer Research 39, Apr. (1979), pp. 1339-1346.
"Synthesis and Properties of Some 13-cis- and All-Trans-Retinamides", Shealy et al., J. of Pharm. Sci., vol. 73, No. 6, Jun. (1984), pp. 745-751.
"A Novel Peptide Synthesis", Zaoral and Arnold, Tetrahedron Letters, No. 14 (1960), pp. 9-12.

Affiliated with

Also associated with

Rating

Process for preparing retinoyl chlorides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing retinoyl chlorides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing retinoyl chlorides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1319374