Transdermal delivery of basic drugs using nonpolar adhesive syst

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424449, A61F 1302

Patent

active

058797017

ABSTRACT:
Solubilization enhancer compositions are provided which facilitate transdermal administration of basic drugs from transdermal systems composed of nonpolar adhesive materials. Preferred solubilization enhancer compositions are comprised of liquid, isomeric acid mixtures such as oleic acid dimer. The invention also relates to novel transdermal systems, drug reservoirs, formulations, and methods of drug administration, in which the disclosed solubilization enhancer compositions are used.

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