Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1982-09-14
1986-01-28
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544276, 544277, A61K 3152, C07D47330
Patent
active
045671826
ABSTRACT:
The invention relates to a series of purine derivatives of formula (I) ##STR1## wherein R is hydrogen or NH.sub.2, n is an integer from 1 to 6, R.sup.1 is one of the following chains: ##STR2## wherein R.sup.2 is the residue of an aminoacid, R.sup.3 is hydrogen or the residue of an oligopeptide and R.sup.4 is OH or the residue of an oligopeptide.
REFERENCES:
patent: 4360522 (1982-11-01), Schaeffer
J. W. Hadden, "The Immunopharmacology of Purine-Related Compounds", pp. 131-133.
P. Cornaglia-Ferraris, et al; "L-Aminoacid-Hypoxantine Derivatives Identified as Differentiators of Pre-T Cells in nu
u Mice".
A. Melodia, et al; "L-Arginine and L-Arginine Derivatives Identified as Activators of Human PMN-Leukocyte `In Vitro`".
P. Cornaglia Ferraris, "Substituted Purines as Immunomodulators: Speculative Considerations"; EOS n. 2, vol. IV (1984).
p. A-829 from Italian Pharmaceutical Directory.
p. 4853 From the Merck Index, 9th Edition.
Gilman "Organic Chemistry", vol. 2, p. 1079 (1943).
Co Pharma Corporation S.r.l.
Rizzo Nicholas S.
LandOfFree
Compounds endowed with immunomodulating activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds endowed with immunomodulating activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds endowed with immunomodulating activity will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1306455