Imidazoline derivatives as .alpha..sub.2 -antagonists

Details Imidazoline derivatives as .alpha..sub.2 -antagonists Imidazoline derivatives as .alpha..sub.2 -antagonists

1984-10-16

1986-01-28

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

2602456, 514294, 546 94, A61K 3155, A61K 3147, C07D47106, C07D48706

Patent

active

045671770

ABSTRACT:
Imidazoline derivatives of formula (I) ##STR1## in which n is 1 or 2, R is hydrogen, C.sub.1 -C.sub.3 alkyl or allyl group, and X is hydrogen, halogen atom, methyl or methoxy, in the form of enantiomers or mixtures thereof, and their pharmaceutically acceptable acid addition salts are useful as .alpha..sub.2 -antagonists.

REFERENCES:
patent: 4411908 (1983-10-01), Chapleo et al.
Buehler and Pearson, Survey of Organic Syntheses, vol. I, Wiley & Sons 1977, pp. 836-837.
March, Advanced Organic Chemistry, 2d ed., McGraw Hill, pp. 422-423 and 1125.

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