Process for preparing auranofin

Details Process for preparing auranofin Process for preparing auranofin

1977-06-30

1978-11-14

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 4, 536122, C07H 2300

Patent

active

041257111

ABSTRACT:
Auranofin is prepared by reacting 1-.beta.-D-thio-2,3,4,6-tetra-O-acetylglucose with a triethylphosphine gold mercaptide.

REFERENCES:
patent: 3635945 (1972-01-01), Nemeth et al.
Coates et al., Aust. J. Chem. 19, 539-545 (1966).
Sutton et al., J. Med. Chem., 15, 1095 (1972).

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