Mutants of bone morphogenetic proteins

Details Mutants of bone morphogenetic proteins Mutants of bone morphogenetic proteins

1996-10-31

1998-09-08

Kemmerer, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 530333, 530399, 530350, C07K 1400, C07K 1451, C12N 1511

Patent

active

058044167

ABSTRACT:
DNA molecules encoding mutant forms of bone morphogenetic proteins (BMP) are disclosed. The mutant forms of BMP can be produced bacterially and refolded to produce biologically active homodimers or heterodimers of BMP. A method of making such mutant BMPs is also disclosed.

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