Antifungal 1-substituted benzimidazoles

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424270, C07D41700

Patent

active

040175049

ABSTRACT:
New water soluble benzimidazoles with a high degree of stability, which are substituted at the 1-position with carboxyalkoxycarbonyl substituents and at the 2-position with a 4-thiazolyl group are effective fungicides and anthelmintics. The compounds as well as processes for their preparation are described along with antifungal and anthelmintic compositions for their use. The 1-position substituent is a carboxyalkoxycarbonyl group of from 3 to 11 carbon atoms including certain salts and derivatives of the carboxy group. The compounds are generally prepared by contacting a 1-unsubstituted benzimidazole with a protected carboxyalkoxycarbonyl chloride.

REFERENCES:
patent: 3055907 (1962-09-01), Brown et al.
patent: 3928372 (1975-12-01), Bochis et al.

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