Process for the preparation of 1-(m- and p-hydroxyphenyl)-2-amin

Details Process for the preparation of 1-(m- and p-hydroxyphenyl)-2-amin Process for the preparation of 1-(m- and p-hydroxyphenyl)-2-amin

1972-06-20

1976-06-29

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260566A, C07C 8511

Patent

active

039668134

ABSTRACT:
The present invention relates to a process for the preparation of 1-(m- and p- hydroxyphenyl)-2-aminoethanol which consists of converting an m- or p- hydroxyacetophenone to an isonitrosoketone followed by hydrogenation of the isonitrosoketone. These compounds are sympathomimetics which produce vasoconstricting and cardiotonic effects.

REFERENCES:
patent: 1877795 (1932-09-01), Bockmuhl et al.
patent: 1995709 (1935-03-01), Hartung
patent: 2505645 (1950-04-01), McPhee
patent: 3028429 (1962-04-01), Wilbert et al.
patent: 3088978 (1963-05-01), Brunner et al.
patent: 3253034 (1966-05-01), McLoughlin
patent: 3634519 (1972-01-01), Bentz et al.

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