Process for the production of optically active (R)-(-)-3-halo-1,

Details Process for the production of optically active (R)-(-)-3-halo-1, Process for the production of optically active (R)-(-)-3-halo-1,

1989-11-20

1990-07-24

Rosen, Sam

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435280, C12P 718

Patent

active

049435280

ABSTRACT:
A process for the production of an optically active (R)-(-)-3-halo-1,2-propanediol which comprises contacting a 1,3-dihalo-2-propanol with a dehalogenase originating from a microorganism belonging to the genus Corynebacterium or Microbacterium. This process makes it possible to produce the (R)-(-)-3-halo-1,2-propanediol, which is highly useful as a starting material in the synthesis of various drugs and physiologically active substances, theoretically at a yield of 100%.

REFERENCES:
Takahashi et al--Chem. Abst., vol. 108 (1988), p. 166,128w.

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