Process for the preparation of 5'-substituted 2-(3'-thienyl)prop

Details Process for the preparation of 5'-substituted 2-(3'-thienyl)prop Process for the preparation of 5'-substituted 2-(3'-thienyl)prop

1986-01-14

1987-09-01

Siegel, Alan

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514438, 549 72, 549 79, A61K 3138, C07D33322, C07D33324

Patent

active

046909451

ABSTRACT:
The present invention relates to the preparation of compounds, useful in animals and in humans, as nonsteroid anti-inflammatory agents of the formula ##STR1## in which R.sub.1 is hydrogen, alkyl, alkanoyl, phenylalkyl or phenylalkanoyl, said alkyl and alkanoyl groups having 1 to 6 carbon atoms and said phenyl group having 1 to 3 halogen substituents or 1 to 3 alkyl or alkoxy substituents, said alkyl or alkoxy substituents having 1 to 4 carbon atoms, and their pharmaceutically acceptable salts.

REFERENCES:
patent: 4159986 (1979-07-01), Clemence
Wagner, Syn. Org. Chem. 1965, pp. 426-429.

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