4-Aminoalkyl-7-hydroxy-2(3H)-indolones

Details 4-Aminoalkyl-7-hydroxy-2(3H)-indolones 4-Aminoalkyl-7-hydroxy-2(3H)-indolones

1980-08-22

1982-02-09

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26032616, 424274, C07D20914, A61K 3140

Patent

active

043149448

ABSTRACT:
A new group of 2(3H)-indolones whose structures are characterized by having an aminoalkyl substituent at position 4 and a hydroxy group at position 7 of the indolone nucleus have beneficial activity on the cardiovascular system. A typical species of the group is 4-di-n-propylaminoethyl-7-hydroxy-2(3H)-indolone and its acid addition salts.

REFERENCES:
patent: 3280145 (1966-10-01), Hofmann et al.
patent: 3644403 (1972-02-01), Canas-Rodriquez
patent: 4053613 (1977-10-01), Rounyak et al.
Walker et al., J. Med. Chem. 13, pp. 983-985 (1970).
Loudon et al., Chem. Abst., 50, p. 4963 (1956).
Wahl, Chem. Abst., 12, p. 2196 (1918).
Yoshizaki et al., J. Med. Chem., 19, pp. 1138-1141 (1976).
Yoshizakai et al., J. Med. Chem., 20, p. 1103-1104 (1977).

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