Methods for the treatment of cancer

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

549510, 549511, 424649, C07D30514

Patent

active

061503983

ABSTRACT:
A pharmaceutical composition comprising an effective cancerous cell growth inhibiting amount of paclitaxel, or a paclitaxel derivative, and an effective cancerous cell growth inhibiting amount of an active agent which inhibits cancerous cell growth by exerting an effect on mammalian cell cycle during G.sub.1 or S-phase of the cell division cycle to inhibit said cancerous cell growth and methods of using same.

REFERENCES:
patent: 4357352 (1982-11-01), Swallow
patent: 4535058 (1985-08-01), Weinberg et al.
patent: 4569916 (1986-02-01), Penman et al.
patent: 4701406 (1987-10-01), Chou
patent: 4798787 (1989-01-01), McCormick et al.
patent: 4814470 (1989-03-01), Colin et al.
patent: 4820631 (1989-04-01), Lacal et al.
patent: 4871838 (1989-10-01), Bos et al.
patent: 4885238 (1989-12-01), Reddel et al.
patent: 4942184 (1990-07-01), Huagwitz
patent: 4960790 (1990-10-01), Stella et al.
patent: 4996145 (1991-02-01), Weisenthal
patent: 5034544 (1991-07-01), Elliott
patent: 5114951 (1992-05-01), King
patent: 5124330 (1992-06-01), King
patent: 5124338 (1992-06-01), King
patent: 5124339 (1992-06-01), King
patent: 5160727 (1992-11-01), Klohs et al.
patent: 5208238 (1993-05-01), King
patent: 5262409 (1993-11-01), Margolis et al.
patent: 5300282 (1994-04-01), King
patent: 5346897 (1994-09-01), King
patent: 5364843 (1994-11-01), King
patent: 5387685 (1995-02-01), Powell et al.
patent: 5395610 (1995-03-01), King
patent: 5447936 (1995-09-01), Hausheer et al.
patent: 5449663 (1995-09-01), Bicher
patent: 5468754 (1995-11-01), Hausheet et al.
Boven, et al., Cancer Research, 45, 86-90 (1985).
Du Bois et al., Seminars in Oncology, 24 (5), S15-44-S15-52 (1997).
Eisenberger, et al. J. Clin. Oncol., 7 (9), 1341-1345 (1989).
Gadduci et al., Anticancer Research, 17, 4703-4708 (1997).
Hannan et al., Toxicology, 55, 183-191 (1989).
Holmes et al., J. Natl. Cancer Inst., 83 (24), 1979-1805 (1991).
Kavanagh, Cancer Bulletin (Houston), 42 (2), 89-93 (1990).
Kelsen et al., Seminars in Oncology, 24 (6), S19-77-S19-81 (1997).
Maugh, Science, 194, 310 (1976).
McGuire et al., Annals of Internal Medicine, 111 (4), 273-279 (1989).
Micetich et al., Cancer Research, 45, 4043-4047 (1985).
Nio, et al. J. Surg. Oncol., 48, 252-259 (1991).
Ringel et al., J. Natl. Cancer Inst., 83 (4), 288-291 (1991).
Rowinsky et al., Proc. Am. Soc. Clin. Oncol., 7, 136 (1988).
Salmon, et al., J. Clin. Oncol., 12 (11), 2405-2414 (1994).
Sorensen, Seminars in Oncology, 24 (4), S12-18-S12-20 (1997).
Allende et al., FEBS Lett., 234, 426-430 (1988).
Barbacid, Ann. Rev. Biochem., 56, 779-827 (1987).
Barber, Yale Journal of Biology and Medicine, 64, 127-141 (1991).
Barrett et al., Mol. Cell Biol., 10, 310-315 (1990).
Birchmeier et al., Cell, 43, 615-621 (1985).
Bravo, Cell Growth & Differentiation, 1, 305-309 (1990).
Brewer et al., Cancer Treatment Reports, 71, 353-359 (1987).
Cadman et al., Science, 205, 1135-1137 (1979).
Caldas et al., J. of the National Cancer Institute Monographs, 15, 155-159 (1993).
Caldas et al., Seminars in Oncology, 20, 50-55 (1993).
Chabner et al., Cancer Chemotherapy and Biological Response Modifiers Annual, 11, 74-81 (Elsevier Science Publishers B.V., 1990).
Chackalaparampil et al., Cell, 52, 801-810 (1988).
Citardi et al., Proc. AACR, 31, 410 (1990).
Coughlin et al., Science, 243, 1191-1194 (1989).
Daar et al, Mol. Cell Biol., 11, 5985-5991 (1991).
Daar et al., J. Cell. Biol., 114, 329-335 (1990).
Daar et al., Science, 253, 74-76 (1991).
Delaporte et al., Exp. Cell Res., 197, 176-182 (1991).
Deshpande et al., Mol. Cell Biol., 7, 1285-1288 (1987).
Ducommun et al., Analytical Biochemistry, 187, 94-97 (1990).
Dumont, J. Morphol., 136, 153-180 (1972).
Dunphy et al., Cell, 54, 423-431 (1988).
Durkin et al., Mol. Cell Biol., 7, 444-449 (1987).
Feig et al., Mol. Cell Biol., 8, 3235-3243 (1988).
Fischinger et al., J. Gen. Virol., 13, 203-214 (1971).
Frankel et al., J. Virol., 21, 153-160 (1977).
Freeman et al., Proc. Natl. Acad. Sci. USA, 86, 5805-5809 (1989).
Gautier et al., Cell, 54, 433-439 (1988).
Gautier et al., Cell, 60, 487-494 (1990).
Gerhart et al., J. Cell Biol., 98, 1247-1255 (1984).
Gupta et al., British J. Cancer, 58, 441-447 (1988).
Hagag et al., Oncogene, 5, 1481-1489 (1990).
Hartwell et al., Science, 246, 629-634 (1989).
Heidemann et al., J. Cell. Sci., 77, 129-141 (1985).
Heidemann et al., Dev. Biol., 80, 489-494 (1980).
Hellman et al., Cancer: Principles and Practice of Oncology, 1st Ed., Philadelphia, JB Lippencott, 73-79, 132-155 (1982).
Hirakawa et al., Proc. Natl. Acad. Sci. USA, 85, 1519-1523 (1988).
Jones et al., Proc. Natl. Acad. Sci. USA, 77, 2651-2655 (1980).
Kaplan et al., Cell, 61, 125-133 (1990).
Kazlauskas et al., Science, 247, 1578-1581 (1990).
Kim et al., Mol. Cell Biol., 10, 5945-5949 (1990).
Kishimoto et al., Exp. Cell Res., 137, 121-126 (1982).
Kishimoto et al., J. Exp. Zool., 231, 293-295 (1984).
Korn et al., Science, 236, 840-843 (1987).
Korn et al., J. of Clinical Oncology, 11, 794-801 (1993).
Kypta et al., Cell, 62, 481-492 (1990).
Kumjian et al., Proc. Natl. Acad. Sci. USA, 86, 8232-8236 (1989).
Lacal et al., EMBO J., 5, 679-687 (1986).
Lee et al., Trends in Genetics, 4, 287-290 (1988).
Lohka et al., J. Cell. Biol., 98, 1222-1230 (1984).
Lohka et al., J. Cell. Biol., 101, 518-523 (1985).
Lohka et al., Proc. Natl. Acad. Sci. USA, 85, 3009-3013 (1988).
Margolis et al., Cell, 57, 1101-1107 (1989).
Markman et al., Gynecologic Oncology, 45, 3-8 (1992).
Masui et al., J. Exp. Zool., 177, 129-146 (1971).
Masui et al., Int. Rev. Cytol., 57, 185-282 (1979).
McGuire, J. of the National Cancer Institute, 81, 1438-1439 (1989).
McGuire, Hematology/Oncology Clinics of North America, 6, 927-940 (1992).
McGuire, Gynecologic Oncology, 51, 78-85 (1993).
McGuire, Cancer Supplement, 71, 1541-1550 (1993).
McGuire III et al., J. of Clinical Oncology, 7, 1462-1468 (1989).
Meyerhoff et al., Dev. Biol., 61, 214-229 (1977).
Miake-Ley et al., Cell, 41, 165-175 (1985).
Morrison et al., Cell, 58, 649-657 (1989).
Murray et al., Nature, 339, 275-280 (1989).
Murray et al., Science, 246, 614-621 (1989).
Murray et al., Nature, 339, 280-286 (1989).
Newport et al., Cell, 30, 675-686 (1984).
Newport et al., Cell, 37, 731-742 (1984).
O'Keefe et al., Proc. Natl. Acad. Sci. USA, 86, 7038-7042 (1989).
Oskarsson et al., Science, 207, 1222-1224 (1980).
Papkoff et al., Cell, 29, 417-426 (1982).
Pardee et al., Science, 246, 603-608 (1989).
Park et al., The Metabolic Basics of Inherited Disease, 1, Chapter 5, 251-276 (Scriver et al., eds.) (McGraw-Hill New York, 1989).
Paules et al., Proc. Natl. Acad. Sci. USA, 86, 5395-5399 (1989).
Propst et al., Nature, 315, 516-518 (1985).
Ridley et al., EMBO J., 7, 1635-1645 (1988).
Rollins et al., Adv. Cancer Res., 53, 1-32 (1989).
Rowinsky et al., Proc. ASCO, 9, (1990).
Rowinsky et al., J. Clin. Oncol, "Sixth International Symposium on Platinum and Other Metal Coordinatio Compounds in Cancer Chemotherapy", University of California, San Diego Cancer Center (1991).
Rowinsky et al., J. of Clinical Oncology, 9, 1692-1703 (1991).
Rowinsky et al., J. of Clinical Oncology, 9, 1704-1712 (1991).
Roy et al., Cell, 61, 825-831 (1990).
Rubinstein et al., J. Nat'l Cancer Inst., 82, 1113-1118 (1990).
Sagata et al., Nature, 335, 519-525 (1988).
Sagata et al., Science, 245, 643-646 (1989).
Sagata et al., Nature, 342, 512-518 (1989).
Schiff et al., Nature, 277, 665-667 (1979).
Schiff et al., Proc. Natl. Acad. Sci. USA, 77, 1561-1565 (1980).
Skehan et al., J. Nat'l Cancer Inst., 82, 1107-112 (1990).
Smith et al., Dev. Biol., 25, 232-247 (1971).
Tachibana et al., J. Cell Sci., 88, 273-282 (1987).
Trimble et al., Gynecologic Oncology, 55, S114-S121 (1994).
Vale, Cell, 64, 827-839 (1991).
Vande Woude et al., 1990 Views of Cancer Research, General Motors Research Foundation, 128-143 (1990).
Vogt et al., Adv. Cancer Res., 55, 1-35 (1990).
Watanabe et al., Nature, 342, 505-511 (1989).
Willumsen et al., EMBO J., 3, 2581 (1984).
Wilson et al., Carcinogenesis, 10, (4), 635-640 (1989).
Zhou et al., Science, 251, 671-675 (1991).
Jekunen et al., "Synergistic interaction between cisplatin and taxol in human ovarian carcinoma

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods for the treatment of cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for the treatment of cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for the treatment of cancer will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1257791

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.