Antibiotic for methicillin resistant bacteria

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 86, 544243, 544320, 544321, 5483141, 548465, 564 59, 564152, 564155, 564230, 564231, A61D 31513, C07D23922

Patent

active

061109258

ABSTRACT:
The present invention is directed to anti-bacterial and anti-tumor agents and the synthesis thereof.

REFERENCES:
Funabashi Y., et al. "A New Anti-MRSA Dipeptide, TAN-1057 A", Tetrahydron, vol. 49, No. 1, 1993, pp. 13-28.
Katayama N., et al. "TAN-1057 A-D, New antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus", J. Antibiot., vol. 46, No. 4, 1993, pp. 606-613.
Yuan C., et al. "Total Synthesis of the Anti Methicillin-Resistant Staphylococcus aureus Peptide antibiotics TAN-1057 A-D", J. Am. Chem. Soc., vol. 1997, No. 49, 1997, pp. 11777-11784.
Tian, Z., et al. "Synthesis of optically pure Ca-methyl-arginine", Int. J. Peptide Protein Res., 40, 1992, 119-126.
Yuan C., et al. "An efficient method for the preparation of amidinoureas", Tetrahedron Letters, vol. 37, No. 12, pp. 1945-1948, 1997.

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